Mechanism of MEBT/MEBO Anti-Infection

Infection is the main reason of death in burns patients, especially extensive burns patients. 

It is also one of the four technical difficulties in traditional burns therapy. 

MEBT takes advantage of non-bactericidal and drainage method to achieve the goal of anti-infection. 

MEBT/MEBO attains its anti-infection mechanism via the following procedures:

First, it controls infection by maintaining smooth drainage on wounds. 

This is achieved by the self drainage effect of MEBO on wounds; redressing every 4 to 6 hours, immediate removal and clean of liquefied necrotic tissues in deep wounds; and the immediate application of 'Ploughing Method', 'Thinning method in necrotic tissues' to remove necrotic tissues in time. 

At the same time, viable tissues were not damaged, thus decrease the absorption of necrotic tissues and toxins and reduce the occurrence of sepsis. 

This is the core and one of the main measures to ensure MEBT could effectively control infection.

Second, the anti-infection mechanism is achieved by controlling bacteria in a bio-control method. 

The laboratory research and clinical application revealed that in the micro-environment formed by MEBO, non-genetic heteromorphosis could occur in bacteria, the metabolism and reproduction rate slows down, the amount decreased, thus the bacteria toxicity decreased. 

It could also prevent the invasion of other bacteria. This bacteria bio-control method, which decreases the proportion of bacteria tissue and normal tissue, is also a basic principle for MEBT to achieve anti-infection effect.

Third, a great amount of lipid ingredients in MEBO provide the raw material and energy source for skin regeneration, especially the synthesis of cell membrane. 

These ingredients not only save local dying cells, but also provide raw material and energy for proliferation of skin stem cells and local activities of immunological cells after they were absorbed into blood. 

The recovery of dying cells and regenerated new cells could form a tissue barrier, prevent the invasion of microbes and swallow necrotic tissues and bacteria.

Forth, the pharmaceutical ingredient in MEBO, β-sitosterol, could exert anti-inflammation effect like glucocorticoid after being absorbed into blood. 

Therefore decrease the occurrence rate of SIRS and increase the body's non-specific immunity.


The anti-infection effect of MEBT/MEBO only means omit the necessity of applying antibiotics locally, it does not mean to get rid of the principle of applying antibiotics systemically. 

Systemic antibiotics application should be carried out according to different clinical conditions while the principle of early, powerful and short-term application is emphasized.