MEBT/MEBO in treating Penis and Scrotum skin soft tissue laceration

Male external genital organs mainly consist of penis and scrotum. Because the parts are located at concealed positions and have more wrinkles, it is not easy to remove necrotic tissue layers on wounds[2] after injured

However, the application of MEBO can liquefy and discharge the necrotic tissues on wounds to guarantee the clear and free drainage of the wounds. Simultaneously, a moist physiological environment is formed around the wounds, which starts the growth of stem cells on wounds to regenerate skin tissues in situ . 

This ensures the wounds healing in the shortest time. The average healing time of the treatment group was 7.5 days.

1. Penis and scrotum at perineum, as one of the sensitive parts of human body, are easy to feel violently pain after injured for there are abundant blood vessels, nerves and voluntary muscles. MEBO supplies a moist physiological environment around the wounds which can protect the pain nerve terminals from the stimulations of dry environment and improve the microcirculation of tissues to abate the stimulations and pressures toward the nerve terminals caused by hypoxia and edema. 

As a result, MEBO, with acesodyne and anti -itch functions, can quickly lessen the pain of the wounds. 

After drug application, cases with pain alleviated in 5 minutes account for 63.88% of the treatment group.

2. Penis and scrotum at perineum are the areas easy to be contaminated by stool and urine. 

The application of MEBO can not only protect and isolate the wounds from direct contaminations by stool and urine to reduce the contaminative chances of wound environment, but also can freely drain, prevent and treat internal issues and the infections caused by liquefied matters on the wounds to provide an environment as flowing water does not get stale to the wounds.

The moist environment can help liquefy and discharge the necrotic tissues from the superficies to the interior to avoid the absorbtion of toxins through the wounds, so it provides a fine environment for the viability of survival epidermis tissues. β—sitosterol and other components contained in MEBO have anti-inflammatory action because they interact with substrate to make bacterium mutate and lose toxicity quickly to become non-invasiveness. 

MEBO can inhibit and control the growth and reproduction of all the general pathogens to achieve the anti-inflammatory functions[3]. The infection rate of the treatment group was merely 5.55%.

MEBO can reduce inflammatory reaction of wounds and overcome the negative stimulations to the wounds that treated by occlusive dressing, during which the wounds are will mechanically injured when wound dressings are changed, so it lessens the scar formation on the wounds. 

MEBO can get rid of hyper-oxyradical which impacts the stability of tissues, better the partial environment of oxygen supply around the wounds and promote the integrative healing of the wounds so as to reduce scar formation. 

MEBO regulates and controls the hyperplasia and arrangement order of celluloses to make epithelium of survival glands regenerate and differentiate to basal layer cells in surface layer, and finally the wounds epithelized healgradually.

This complies to the rules of skin natural regenerative repair, reduces scar hyperplasia[4] and obviously decreases the disability rate. 

Three cases in the control group while none in the treatment group underwent erection dysfunction caused by the contracture and malunion of the scars on the penis.

In the treatment group, the side effects of local discomfort, such as contact dermatitis and pain caused by MEBO were evidently lower than that in the control group. 

This shows that MEBO is the preferred external used medicine because it provides an ideal effect with low side effect in treating contused & lacerated wounds of the skin soft tissues.

MEBT/MEBO is the best method for treating penis and scrotum skin soft tissue laceration.

Full Report:

Experience with MEBT/MEBO in treating penis and scrotum skin soft tissue laceration, The Chinese Journal of Burns Wounds and Surface Ulcers 2003, (4): 330-332