Treatment of Toxic Epidermal Necrolysis with Moisture-Retentive Ointment: A Case Report and Review of the Literature

Atiyeh BS, et al. Dermatol Surg. 2003; 29(2):185-188
A case of TEN has been successfully managed with the application of a MEBO. In addition to its antibacterial effect, the ointment provides the necessary moist environment for optimal speedy healing by re-epithelialization, protects denuded yet undamaged dermis, and induces rapid cutaneous barrier function restoration. All of these positive actions on anatomical as well as on physiologic healing provided by one single agent, in addition to the practical method of application without the need for labor-intensive and cumbersome dressings except rarely, are obvious advantages for the use of MEBO over other products and agents in the management of Stevens-Johnson Syndrome and TEN.